JEE Main · 2011 · 10 Apr 2011 · Offline · Biomolecules

The presence or absence of hydroxyl group on which carbon atom of sugar differentiates RNA and DNA ?

(A) $2^{nd}$ ✓ Correct
(B) $3^{rd}$
(C) $4^{th}$
(D) $1^{st}$

Answer: (A)

Solution

RNA is built on ribose and DNA on 2-deoxyribose, and the single difference between these sugars is at the

2^{'}

carbon: ribose carries a hydroxyl group there, whereas in deoxyribose that position holds only hydrogen. So it is the presence or absence of the

- OH

on the second carbon of the sugar that distinguishes RNA from DNA.

JEE Main · 2011 · 10 Apr 2011 · Offline · Single correct option

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