Define the term denaturation in relation to proteins.
Solution
When a native protein is heated or its pH changed, the hydrogen bonds maintaining its shape break: globules unfold, helices uncoil, and biological activity is lost — this is \textbf{denaturation}. Secondary and tertiary structures are destroyed; the primary sequence stays intact (boiled egg white).
CBSE Class 12 Board · 2000 · Delhi · Subjective