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JEE Main · 2020 · 04 Sep 2020 · Shift 2 · Chemistry in Everyday Life

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The mechanism of action of "Terfenadine" (Seldane) is :
  1. (A)Inhibits the action of histamine receptor✓ Correct
  2. (B)Inhibits the secretion of histamine
  3. (C)Helps in the secretion of histamine
  4. (D)Activates the histamine receptor

Answer: (A)

Solution

Terfenadine (Seldane) is an antihistamine, and like other drugs of its class it acts by occupying the histamine receptors so that histamine itself cannot bind and trigger the allergic response. It does not change how much histamine is made or released; it simply blocks the receptor, so its action is to inhibit the histamine receptor.

JEE Main · 2020 · 04 Sep 2020 · Shift 2 · Single correct option

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