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JEE Main · 2022 · 26 Jun 2022 · Shift 1 · Chemistry in Everyday Life

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A chemical which stimulates the secretion of pepsin is :
  1. (A)Anti histamine
  2. (B)Cimetidine
  3. (C)Histamine✓ Correct
  4. (D)Zantac

Answer: (C)

Solution

Histamine is a chemical messenger that stimulates the secretion of pepsin and hydrochloric acid (HCl) in the stomach. It acts on H₂ receptors in the gastric parietal cells to promote acid secretion. Antihistamines like cimetidine and Zantac (ranitidine) are H₂ receptor antagonists that block histamine's action and reduce acid secretion.

JEE Main · 2022 · 26 Jun 2022 · Shift 1 · Single correct option

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